The main use for this bullet is Alaska. It can comfortably reach 2400 to 2500fps from a 458 Winchester Magnum, depending on barrel length. That combination will smite, with finality, any and all beasts found within that state. Moose and big bear of any size will have met their match. It would also be suitable for much of Africa but, due to the sectional density, I would leave the Cape buffalos to the 458-450 grain bullet.